Fish oil and ischaemic heart disease.
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چکیده
منابع مشابه
Fish oil and ischemic heart disease.
Fish oil products are available with or without prescription and are widely used by patients with ischaemic heart disease (IHD). The interest in fish oils, rich in the long chain n-3 polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (n-3 20:5) and docosahexaenoic acid (n-3 22:6), originates primarily from the pioneering work of Dyerberg and Bang.' Prompted by the low incidence of acute ...
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T he antithrombotic action of aspirin depends on inhibition of cyclooxygenase activity' in platelets, thereby reducing thromboxane A2 formation and consequently, their aggregability. In 1978, two important concepts on eicosanoid formation were presented. The first2 was that the vascular wall could utilize endoperoxides released by adhering platelets for the formation of prostacyclin. The second...
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It has been shown that ischaemic heart disease tends to be associated with elevated levels of serum cholesterol, both in populations (Keys et al., 1958) and in individuals (Kannel et al.,. 1961). There is also evidence that population levels of serum cholesterol are sometimes correlated with (among other characteristics) a high intake of animal fats and a relatively low intake of unsaturated ve...
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Ischaemic heart disease accounts for nearly half of the global cardiovascular disease burden. Aetiologies relating to heart disease are complex, but dyslipidaemia, oxidative stress and inflammation are cardinal features. Despite preventative measures and advancements in treatment regimens with lipid-lowering agents, the high prevalence of heart disease and the residual risk of recurrent events ...
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The overwhelming dominance of the lipid hypothesis for atheroma has obscured the compelling evidence-some of it of many years standing' but some that is more recent2 3 -that both platelets and the coagulation system also contribute to the lesion. There is much epidemiological evidence4 5 of some other process besides atherogenesis to account for the clinical manifestations of coronary artery di...
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ژورنال
عنوان ژورنال: Heart
سال: 1993
ISSN: 1355-6037
DOI: 10.1136/hrt.70.3.212